Name J. David Van Horn Ph.D.
Dr. Van Horn's lab is investigating the bioinorganic chemistry of two elements, uranium and chromium. His lab is interested in quantitative aspects of the kinetics and thermodynamics of these metals complexing with biological ligands. In the bloodstream, uranium is complexed almost completely by carbonate; his team is describing the U-peptide or U-protein interactions that describe the transport of U in the blood serum. Recently, Dr. Van Horn's lab described interactions of the uranyl cation with a short peptides which led them to a model of non-specific transport in serum, and continue to study U-peptide complexes. His lab is also exploring the fundamental coordination chemistry of chromium as it applies to the expected forms of Cr in vivo, its transport in the bloodstream, its excretion, and its potential pharmacological action in the human body. The lab has completed a bioinformatics study to locate the origin of Cr-peptide complexes in the body, and has made some new Cr-peptide complexes.
Flarsheim Hall 510F
Personal Web Page
Point Loma Nazarene University, BA(summa cum laude, Chemistry
University of Utah, Salt Lake City, UT, PhD, Organic and Biological Chemistry
University of California, Berkeley, and Post-doctoral training, Inorganic Chemistry, Lawrence Berkeley National Laboratory
College of Arts & Sciences
Biological chemistry of metal ions, especially heavy metals & actinides (lead, polonium, radon, etc)